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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Epidemiology. 2018 Sep;29(5):658–665. doi: 10.1097/EDE.0000000000000867

Table 2.

Deaths per 1000 under no intervention (“natural course”) and deaths delayed or prevented by age 80 per 1000 workers for a series of hypothetical occupational exposure limits, 65,999 silica exposed workers across 10 pooled cohorts from the United States, South Africa, Australia, Finland, and China, 1919–1998.

Deaths delayed or prevented per 1000 workers Years of life saved (all causes)


Lung cancer Other causes All causes

Natural coursea 0 (ref) 0 (ref) 0 (ref) 0 (ref)
 100 ug/m3 1.71 (−0.814, 4.24) 8.77 (2.65, 14.9) 10.5 (4.40, 16.6) 3859 (2122, 5598)
 50 ug/m3 2.47 (0.216, 4.72) 11.7 (5.58, 17.7) 14.1 (8.34, 19.9) 5158 (3409, 6906)
 25 ug/m3 3.03 (0.927, 5.14) 13.3 (6.57, 20.0) 16.3 (9.99, 22.7) 6337 (4614, 8060)
 10 ug/m3 3.41 (1.30, 5.52) 15.2 (9.02, 21.3) 18.6 (12.6, 24.5) 7067 (5195, 8940)
 Eliminate exposure 3.91 (1.53, 6.30) 16.8 (10.4, 23.1) 20.7 (14.5, 26.8) 7857 (5891, 9823)
a

Under the natural course, deaths per 1,000 workers by age 80 (95% CI) were 30.3 (29.3, 31.3) for lung cancer and 359 (356, 362) for all other causes.