pAktT308 in epitrochlearis muscles. A) For muscles incubated without insulin, RM 2-way ANOVA indicated a main effect of serum* (p<0.001) and a main effect of AICAR# (p<0.05). Post hoc analysis revealed pAktT308 with prior serum > No AICAR or seruma (p<0.001), prior AICAR > No AICAR or serumb (p<0.01), and prior serum & AICAR > AICAR aloned (p<0.001). For muscles incubated with insulin, RM 2-way ANOVA indicated a main effect of serum* (p<0.001). Post hoc analysis revealed pAktT308 with prior serum > No AICAR or seruma (p<0.05) and prior serum & AICAR > AICAR aloned (p<0.01). B) Two-way ANOVA indicated a main effect of insulin (p<0.001). Post hoc analysis revealed pAktT308 with Iinsulin > No AICAR or serum (p<0.001), and IAICAR+insulin > AICAR alone (p<0.001).