Table 2.

Brain regions showing greater and less activity in patients with ASD and healthy controls in the pooled meta-analysis (voxel-wise p < 0.005 and full-width at half-maximum 20 mm).

	Maximum			Clusters
Brain Regions	MNIcoordinates x, y, z	SDM value	p-value	No. voxel	Breakdown (no. of voxels)
ASD > CONTROL
R supplementary motor area	8, −16, 72	1.399	0.001807332	58	R supplementary motor area, BA 6, BA 4(58)
R inferior/middle frontal gyrus	48, 12, 30	2.257	0.000014424	412	R inferior frontal gyrus, opercular part, BA 44, BA 48, triangular part, BA 48 (378) R middle frontal gyrus, BA 44, BA 45 (30) R precentral gyrus, BA 44 (4)
L precentral gyrus	−20, −14, 62	1.627	0.00055635	59	L precentral gyrus, BA 6(40) L paracentral lobule, BA 6(12) L superior frontal gyrus, dorsolateral, BA 6(6) L supplementary motor area, BA 6(1)
R cerebellum, hemispheric lobule IX	10, −58, −48	1.457	0.001313925	304	R cerebellum, hemispheric lobule IX(207) VIII(97)
L cerebellum, hemispheric lobule IX	−2,−54,−56	1.39	0.001901269	369	L cerebellum, hemispheric lobule IX(123) VIII(246)
ASD < CONTROL
L precuneus, median cingulate / paracingulate gyri	−6, −48, 36	−2.207	0.00034678	276	L precuneus, BA 23(166) L median network, cingulum(41) L median cingulate / paracingulate gyri, BA 23(37) L posterior cingulate gyrus, BA 23(32)
R middle temporal gyrus	54,−44, 4	−2.632	0.000052631	595	R middle temporal gyrus, BA 22, BA 21, BA 42, BA 41(330) R superior temporal gyrus, BA 42, BA 22, BA 41, BA 21(263) R angular gyrus, BA 41(1) R supramarginal gyrus, BA 41(1)
R cerebellum, crus I	46, −54, −32	−2.158	0.000437617	493	R cerebellum, crus I, BA 37, BA 39,(439) II,(21) hemispheric lobule VI, BA 37, BA 19(15) R fusiform gyrus, BA 37(10) R inferior temporal gyrus, BA 37(8)
L cerebellum, crus I	−40, −70, −28	−2.048	0.000755548	284	L cerebellum, crus I, BA 19, BA 37,(275) II(1)
					L cerebellum, hemispheric lobule VI, BA 37, BA 19(8))

BA, Brodmann area; L, Left; MNI, Montreal Neurological Institute; R, right; SDM, signed differential mapping.