Table 5.
Transcript expression of ion channels and their regulators.
| mRNA counts | Fold change with respect to Control | ||
|---|---|---|---|
| Gene | Control | LPS | I+T |
| Calm1 (CaM) | 13457 ± 2110 | 5.96 ± 1.40↑↑↑*** | 1.75 ± 0.19↑↑↑ |
| Kcna2 (Kv1.2) | 42 ± 30 | 0.63 ± 0.55 | 0.12 ± 0.07↓↓∗ |
| Kcna3 (Kv1.3) | 71 ± 11 | 1.97 ± 0.69↑↑ | 2.30 ± 0.47↑↑↑ |
| Kcna5 (Kv1.5) | 3 ± 1 | 6.40 ± 6.62 | 1.73 ± 1.10 |
| Kcnj2 (Kir2.1) | 1239 ± 386 | 9.04 ± 1.45↑↑↑** | 5.13 ± 0.92↑↑↑ |
| Kcnma1 (BK) | 4 ± 2 | 3.24 ± 1.77* | 0.84 ± 0.70 |
| Kcnn3 (KCa2.3) | 14 ± 10 | 11.39 ± 6.35↑↑↑** | 1.47 ± 0.48 |
| Kcnn4 (KCa3.1) | 31 ± 8 | 1.05 ± 0.96 | 1.99 ± 0.45 |
| Mtmr6 | 541 ± 85 | 3.57 ± 0.62↑↑↑*** | 1.56 ± 0.16↑↑↑ |
| Nme2 (NDPK-B) | 3166 ± 283 | 2.90 ± 0.25↑↑↑*** | 0.87 ± 0.11 |
| Orai1 | 658 ± 104 | 4.56 ± 0.76↑↑↑*** | 1.06 ± 0.11 |
| Orai3 | 280 ± 16 | 3.59 ± 0.79↑↑↑*** | 2.22 ± 0.11↑↑↑ |
| Phtp1 | 581 ± 74 | 2.28 ± 0.41↑↑↑*** | 1.05 ± 0.11 |
| Ptpn6 (SHP-1) | 1626 ± 257 | 1.77 ± 0.27↑↑↑** | 1.20 ± 0.13 |
| Rest | 589 ± 48 | 4.40 ± 0.83↑↑↑ | 3.93 ± 0.37↑↑↑ |
| Slc8a1 (NCX1) | 3699 ± 516 | 0.42 ± 0.14↓↓↓∗∗ | 0.68 ± 0.06↓ |
| Stim1 | 256 ± 23 | 2.04 ± 0.56↑↑↑ | 2.23 ± 0.25↑↑↑ |
| Stim2 | 547 ± 59 | 1.57 ± 0.43↑↑ | 1.25 ± 0.17 |
| Trpm2 | 932 ± 541 | 1.14 ± 0.28 | 1.73 ± 0.42 |
| Trpm4 | 25 ± 3 | 3.43 ± 1.31↑↑↑*** | 1.15 ± 0.26 |
| Trpm7 | 439 ± 26 | 2.54 ± 0.36↑↑↑*** | 1.18 ± 0.06↑ |
Treatments, data presentation and analysis are as in Table 1.