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. 2018 Mar 27;153:101–113. doi: 10.1016/j.antiviral.2018.03.009

Fig. 10.

Fig. 10

2′diF-4′N3-C inhibits reporter Marburg virus (MARV) infection in human primary small airway epithelial cells. (a) Representative dose response curves for R1479 (green circles), 2′F-4′N3-C (blue triangles), and 2′diF-4′N3-C (red squares) against recombinant reporter MARV expressing a green fluorescent protein (ZsGreen1) using a focus forming unit (FFU) assay. FFU assays for R1479 and 2′F-4′N3-C were performed once, and was repeated once for 2′diF-4′N3-C. Data points and error bars indicate the mean value and standard deviation of 4 biological replicates. (b) Representative composite micrographs of MARV GFP+ FFUs in individual wells of a 96-well plate of 2′diF-4′N3-C -treated, MARV-infected SAECs. Concentrations of 2′diF-4′N3-C (in μM) are indicated above each pictured well.