Table 2.
Effect of ABH/NAC on rats renal and hepatic variables.
| Untreated | ABH/NAC | |
|---|---|---|
| Initial body weight (g) | 199.8 ± 3.7 | 197.3 ± 1.9 |
| Body weight at 28 days (g) | 330.3 ± 4.2 | 298.3 ± 7.0* |
| Body weight as % initial (%) | 165.3 ± 2.2 | 146.6 ± 3.6* |
| Plasma urea (mg/dL) | 41.9 ± 3.4 | 48.0 ± 4.8 |
| Urine urea (mg/24 h) | 6.5 ± 0.4 | 5.4 ± 0.5 |
| Proteins (mg/24 h) | 10.7 ± 1.2 | 12.5 ± 1.3 |
| Plasma creatinine (mg/dL) | 0.56 ± 0.2 | 0.57 ± 0.3 |
| Urine creatinine (mg/24 h) | 972.0 ± 87.5 | 941.5 ± 57.1 |
| Creatinine clearance (ml/min) | 1.78 ± 0.3 | 1.76 ± 0.2 |
| Lactate dehydrogenase LDH (U/L) | 1111.0 ± 435.3 | 768.6 ± 188.9 |
| Glutamic-oxalacetic transaminase GOT (U/L) | 60.0 ± 4.5 | 61.0 ± 11.4 |
| Glutamic-pyruvic transaminase GTP (U/L) | 21.7 ± 1.1 | 16.5 ± 2.9 |
*
P < 0.05 U-Mann-Whitney treated vs. non-treated rats (Untreated Rats n = 4 and ABH-NAC rats = 8).