Table 1.
Susceptibilities of bacterial isolates to boldine and its alkaloid derivatives.
| Bacterial isolate | MIC (μM) |
|||
|---|---|---|---|---|
| Boldine | N-SCN | SCN | ||
| S. pneumoniae | R6 | 1000 | 16 | 16 |
| S. pneumoniae | ATCC 6303T | 1000 | 16 | 16 |
| S. mitis | NCTC 12261T | 1000 | 16 | 16 |
| M. tuberculosis | H37Rv | >500 | 15.6 | 15.6 |
| M. tuberculosis | GC 1237 | 31.25 | 7.8 | 7.8 |
| M. tuberculosis | HMS1553 | 31.25 | 1.95 | 3.9 |
| M. tuberculosis | HMS 1292 | 62.5 | 1.95 | 7.8 |
| M. tuberculosis | HMS1278 | >250 | 7.8 | 15.6 |
| M. tuberculosis | HMS 1498 | 31.25 | 3.9 | 7.8 |
| M. tuberculosis | HMS 1500 | >250 | 7.8 | 15.6 |
| M. tuberculosis | HMS 1536 | >250 | 7.8 | 15.6 |
| M. tuberculosis | HMS 1546 | >250 | 7.8 | 7.8 |