Figure 3.
Co-occupancy of the MRU Fraction by MRUCD200/CD200R1 and MRUnot CD200/CD200R1 May Involve Hierarchal Association or the Presence of Two Stem Cell Populations
(A and B) Demonstration of the two options.
(C) Genes with expression patterns that fit with stem cells being in a single hierarchy: expression of genes in MRUCD200/CD200R1 is greater than in MRUnot CD200/CD200R1 at p < 0.05; expression of genes in MRUnot CD200/CD200R1 is 4-fold greater than in CD200+CD200R1− and CD200R1+CD200−.
(D) Gene-expression pattern indicating progenitors: expression of genes in MRUnot CD200/CD200R1 is 2-fold greater than in MRUCD200/CD200R1, CD200+CD200R1− and CD200R1+CD200−.
(E) Gene-expression pattern indicating differentiated cells: expression of genes in CD200+CD200R1− and CD200R1+CD200− is at least 2-fold greater than in MRUnot CD200/CD200R1 with adjusted p ≤ 0.05; expression of genes in MRUnot CD200/CD200R1 is greater that in MRU CD200/CD200R1 at adjusted p ≤ 0.75.
See also Table S2.