Figure 4.

Behavioral Evaluation in Monkeys after Transplantation of EB-DA and FP-DA Neurons

(A) Time course of changes in motor symptom scores of the monkeys injected with culture medium (control group, n = 3), EB-DA neurons (EB-DA group, n = 4), and FP-DA neurons (FP-DA group, n = 3) from MPTP administration to 8 months after transplantation.

(B) Behavioral improvement rate of the three groups after transplantation (0–24 months), which revealed a significant increase in the two groups that received EB-DA or FP-DA neurons. Dotted lines are pre-transplantation baseline scores 11 months after MPTP treatment. Significance compared with control group (Student's t test): ^∗p < 0.05.

Data are represented as means ± SEM (n = 3 animals for the control and FP-DA groups, 4 animals for the EB-DA group). See also Figure S4.