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. 2018 Jul 25;38(30):6628–6639. doi: 10.1523/JNEUROSCI.2152-17.2018

Figure 1.

Figure 1.

t-LTP in adult spino-parabrachial neurons. A, Example of the t-LTP pairing protocol, which involves evoking an action potential in the projection neuron (via intracellular current injection) at a defined interval after the arrival of a primary afferent-mediated EPSP (Δt = tPre − tPost = −10 ms). B, Administration of the pairing protocol (30 times at 0.2 Hz) led to a significant increase in the amplitude of the monosynaptic primary afferent-evoked EPSC in a lamina I spino-parabrachial neuron following dorsal root stimulation.