Table 1.

Socio-Demographics, Mental Health, and Weight in Relation to Telomere Length Change in Latina Women over a 1-Year Period (Base Pairs; n = 82)

Variable	N/total (%)	Telomere length change, years (base pairs) ±standard deviation	P
Socio-demographics
Marital status
Married or with partner	16/81 (19.8)	129.3 ± 459.4	0.80
Not married	65/81 (90.2)	82.4 ± 717.9
Mexican ethnicity (maternal)
Yes	52/82 (60.1)	34.2 ± 679.7	0.29
No (Central American)	30/82 (36.6)	195.8 ± 646.9
Maternal age
≥35	21/82 (25.6)	55.7 ± 667.8	0.21
<35	61/82 (74.4)	106.2 ± 673.7
Weight status
Obese at baseline
Yes	27/74 (36.5)	−188.8 ± 633.0	<0.01
No	47/74 (63.5)	267.7 ± 595.1
Chronic obesity (in the year before baseline and baseline)
Yes	25/77 (32.5)	−188.7 ± 658.9	0.02
No	52/77 (67.5)	198.5 ± 645.1
Chronic obesity (in the 2 years before baseline and baseline)
Yes	21/77 (27.3)	−158.0 ± 671.3	0.048
No	56/77 (72.7)	177.2 ± 645.6
Obese 5–6 years before baseline
Yes	17/77 (22.1)	198.1 ± 1019.4	0.53
No	60/77 (77.9)	82.0 ± 536.9
Abdominal obesity at baseline
Yes	41/71 (57.7)	200.6 ± 768.3	0.25
No	30/71 (42.3)	9.2 ± 550.3
Chronic abdominal obesity (the year before baseline and baseline)
Yes	34/67 (50.7)	181.2 ± 529.5	0.31
No	33/67 (49.3)	6.3 ± 824.3
Incident obesity and cardiometabolic disease
Hypertension (incident or existing)
Yes	6/77 (7.8)	−407.4 ± 464.0	0.03
No	71/77 (92.2)	168.1 ± 643.6
Diabetes (incident or existing)
Yes	4/66 (6.1)	−227.1 ± 462.6	0.35
No	62/66 (93.9)	52.1 ± 587.4
Persistent obesity at follow-up (from telomere collection to 4-5 years follow-up)
Yes	13/69 (18.8)	97.4 ± 229.8	0.92
No	56/69 (81.2)	118.7 ± 85.1
Obese at follow-up
Yes	17/76 (22.4)	42.5 ± 802.2	0.72
No	59/76 (77.6)	111.0 ± 640.4
Loss of weight; from obese to normal/overweight at 4-5 years follow-up
Yes	13/69 (18.8)	−300.3 ± 424.8	0.01
No	56/69 (81.2)	195.5 ± 653.6