Figure 4.

Inheritance structure of EMOD, illustrated for four disease types. Simulations can be run at each layer of specificity. In Generic SEIRS, individuals have generic disease states of susceptible, exposed, infected and recovered (SEIRS) and have properties such as date of birth, current age, sex, location, rates of fertility and mortality and socio-demographic strata, which are inherited by more specific disease models. Transmission mode models, such as airborne, vector or sexual transmission, retain the generic SEIRS disease states, but modify how individuals interact to give rise to transmission events. For example, sexual transmission adds types of sexual relationships and demographically-specific propensities to enter and break them. The HIV model inherits the sexual behavior logic, but over-writes the generic SEIRS disease and interventions with HIV-specific states and interventions.