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. 2018 Jul 26;11:4367–4375. doi: 10.2147/OTT.S171425

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© 2018 Ding et al. This work is published and licensed by Dove Medical Press Limited

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Tiam1 knockdown inhibited the proliferation, migration, and invasion of pancreatic cancer cells.

Notes: (A) Western blot showing Tiam1 expression in BxPC-3 and SW1990 cells upon Tiam1 knockdown. (B) Proliferating capability of transfected cells was evaluated using colony formation assays. (C) A scratch wound healing assay was used to determine the effects of si-Tiam1 on pancreatic cancer cells motility. (D) Migration and invasion of Tiam1 knockdown cells was measured by transwell assay. **P<0.01.

Abbreviations: con, control; Tiam1, T-cell lymphoma invasion and metastasis inducing factor 1.