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. Author manuscript; available in PMC: 2018 Jul 31.
Published in final edited form as: Acta Biomater. 2015 Nov 7;30:1–12. doi: 10.1016/j.actbio.2015.11.007

Figure 4.

Figure 4

ECM-inspired growth factor delivery systems. (A) Strategies for non-covalent attachment of growth factors to exogenous biomatrices, leveraging the natural affinity of growth factors to these materials. (B) Strategies to covalently attach growth factors to exogenous biomatrices using chemical or enzymatic tools. (C) Strategies to employ endogenous ECM as the delivery biomatrix by engineering fusions of growth factors with ECM binding domains. Inset, Schematic of the extracellular growth factor environment.