Fig 3. LDO removes the copy number effect across samples and maintains sensitivity of essential genes.

A) Boxplot of dependency scores across copy number for uncorrected and LDO corrected data. B) The recall curve for essential, nonessential and amplified genes is shown before and after LDO copy number correction in the cell line DAN-G. C) The area under the recall curve is shown across samples for the essential, nonessential and amplified genes.