Table 2.
Comparison of the quality of life, laboratory findings, and pulmonary function among patients with chronic obstructive pulmonary disease (COPD)*
| BMI (kg/m2)
|
P-value | ||||
|---|---|---|---|---|---|
| <18.5 | 18.5–22.9 | 23–24.9 | ≥25 | ||
| Subjects | 37 (2.8) | 562 (42.6) | 354 (26.8) | 367 (27.8) | |
| Index of quality of life | |||||
| EQ-5D | 0.86 ± 0.18 | 0.92 ± 0.12 | 0.93 ± 0.11 | 0.93 ± 0.13 | <0.01 |
| Laboratory test | |||||
| Total serum cholesterol, mg/dL | 167.3 ± 40.5 | 187.1 ± 36.1 | 187.6 ± 36.9 | 189.8 ± 35.1 | <0.01 |
| TG, mg/dL | 126.5 ± 116.3 | 147.4 ± 120.9 | 167.2 ± 102.9 | 191.2 ± 181.9 | <0.01 |
| LDL cholesterol, mg/dL | 109.5 ± 23.4 | 111.4 ± 36.5 | 109.8 ± 38.6 | 113.6 ± 32.0 | 0.93 |
| HDL cholesterol, mg/dL | 49.4 ± 12.2 | 46.8 ± 11.4 | 44.4 ± 11.0 | 42.6 ± 9.5 | <0.01 |
| Lung function | |||||
| FVC, L | 3.4 ± 0.7 | 3.9 ± 0.7 | 4.0 ± 0.8 | 3.9 ± 0.7 | <0.01 |
| FVC, % predicted | 88.9 ± 15.0 | 92.5 ± 12.7 | 91.6 ± 13.0 | 87.4 ± 12.6 | <0.01 |
| FEV1, L | 2.1 ± 0.5 | 2.4 ± 0.6 | 2.5 ± 0.6 | 2.5 ± 0.5 | <0.01 |
| FEV1, % predicted | 76.0 ± 14.8 | 78.7 ± 12.9 | 79.6 ± 13.6 | 77.9 ± 12.0 | 0.18 |
| FEV1/FVC | 0.62 ± 0.07 | 0.63 ± 0.06 | 0.63 ± 0.06 | 0.65 ± 0.05 | <0.01 |
Note:
*
Data are presented as number (%) or mean ± SD.
Abbreviations: EQ-5D, EuroQol-5 Dimensions questionnaire; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglyceride; BMI, body mass index.