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. Author manuscript; available in PMC: 2019 May 29.
Published in final edited form as: Oncology. 2018 May 29;95(2):81–90. doi: 10.1159/000488489

Table 1.

Summary of variables before BMT based on Barrett’s status (N=228)

Covariate Levels Barrett’s status after BMT
P-value
Yes (n=98) No (n=130)

Age at diagnosis (year) median (range) 67 (31 - 103) 67 (28 - 85) .52

Tumor length at diagnosis (cm) median (range) 5 (1 - 13) 5 (1 - 13) .81

Gender Male 93(94.9%) 115(88.5%) .09
Female 5(5.1%) 15(11.5%)

Siewert class Esophagus 13(13.3%) 3(2.3%) <.0001
AEG1 58(59.2%) 55(42.3%)
AEG2 26(26.5%) 72(55.4%)
NA 1(1%) 0

Tumor Histology Subtype SRC 16(16.3%) 19(14.6%) .72
M 1(1%) 2(1.5%)
M&SRC 3(3.1%) 5(3.8%)
NE 3(3.1%) 1(0.8%)
NOS 75(76.5%) 103(79.2%)

Chronic GERD history Yes 60(61.2%) 78(60%) . 85
No 38(38.8%) 52(40%)

Barrett’s before BMT (biopsy) Yes 50(51%) 18(13.9%)
No 48(49%) 112(86.2%) <.0001

Barrett’s length before BMT(endoscopy appearance) LS≥3cm 38(76%) 14(63.6%)
SS<3cm 12(24%) 8(36.4%) <0.0001

Highest dysplasia before BMT (biopsy) HG 34(34.7%) 12(9.2%) <.0001
LG 10(10.2%) 2(1.5%)
None 54(55.1%) 116(89.2%)

Baseline T-staging T1 3(3%) 3(2.3%) .27
T2 15(15.3%) 10(7.7%)
T3 74(75.5%) 109(83.8%)
T4 3(3%) 3(2.3%)
TX 3(3.1%) 5(3.8%)

Baseline N-staging N0 36(36.7%) 51 (39.2%) .37
N1 54(55.1%) 62(47.7%)
N2 3(3.1%) 10(7.7%)
N3 1(1%) 2(1.5%)
NX 4(1.1%) 5(3.8%)

Baseline M-staging M0 88(89.8%) 110(84.6%% .12
M1 6(6.1%) 17(13.1%)
MX 4(4.1%) 3(2.3%)

Baseline staging I 9(9.1%) 5(3.8%) .07
II-III 80(81.6%) 105(80.8%)
IV 6(6.1%) 17(13.1%)
NA 3 (3.1%) 3(2.3%)

Abbreviations: BMT: bimodality therapy, GERD: gastroesophageal reflux disease, M: mucinous, NE: neuroendocrine; NOS: not otherwise specified; NA: not available, SRC: signet ring cell