Table 1.
Covariate | Levels | Barrett’s status after BMT
|
P-value | |
---|---|---|---|---|
Yes (n=98) | No (n=130) | |||
| ||||
Age at diagnosis (year) median (range) | – | 67 (31 - 103) | 67 (28 - 85) | .52 |
| ||||
Tumor length at diagnosis (cm) median (range) | – | 5 (1 - 13) | 5 (1 - 13) | .81 |
| ||||
Gender | Male | 93(94.9%) | 115(88.5%) | .09 |
Female | 5(5.1%) | 15(11.5%) | ||
| ||||
Siewert class | Esophagus | 13(13.3%) | 3(2.3%) | <.0001 |
AEG1 | 58(59.2%) | 55(42.3%) | ||
AEG2 | 26(26.5%) | 72(55.4%) | ||
NA | 1(1%) | 0 | ||
| ||||
Tumor Histology Subtype | SRC | 16(16.3%) | 19(14.6%) | .72 |
M | 1(1%) | 2(1.5%) | ||
M&SRC | 3(3.1%) | 5(3.8%) | ||
NE | 3(3.1%) | 1(0.8%) | ||
NOS | 75(76.5%) | 103(79.2%) | ||
| ||||
Chronic GERD history | Yes | 60(61.2%) | 78(60%) | . 85 |
No | 38(38.8%) | 52(40%) | ||
| ||||
Barrett’s before BMT (biopsy) | Yes | 50(51%) | 18(13.9%) | |
No | 48(49%) | 112(86.2%) | <.0001 | |
| ||||
Barrett’s length before BMT(endoscopy appearance) | LS≥3cm | 38(76%) | 14(63.6%) | |
SS<3cm | 12(24%) | 8(36.4%) | <0.0001 | |
| ||||
Highest dysplasia before BMT (biopsy) | HG | 34(34.7%) | 12(9.2%) | <.0001 |
LG | 10(10.2%) | 2(1.5%) | ||
None | 54(55.1%) | 116(89.2%) | ||
| ||||
Baseline T-staging | T1 | 3(3%) | 3(2.3%) | .27 |
T2 | 15(15.3%) | 10(7.7%) | ||
T3 | 74(75.5%) | 109(83.8%) | ||
T4 | 3(3%) | 3(2.3%) | ||
TX | 3(3.1%) | 5(3.8%) | ||
| ||||
Baseline N-staging | N0 | 36(36.7%) | 51 (39.2%) | .37 |
N1 | 54(55.1%) | 62(47.7%) | ||
N2 | 3(3.1%) | 10(7.7%) | ||
N3 | 1(1%) | 2(1.5%) | ||
NX | 4(1.1%) | 5(3.8%) | ||
| ||||
Baseline M-staging | M0 | 88(89.8%) | 110(84.6%% | .12 |
M1 | 6(6.1%) | 17(13.1%) | ||
MX | 4(4.1%) | 3(2.3%) | ||
| ||||
Baseline staging | I | 9(9.1%) | 5(3.8%) | .07 |
II-III | 80(81.6%) | 105(80.8%) | ||
IV | 6(6.1%) | 17(13.1%) | ||
NA | 3 (3.1%) | 3(2.3%) |
Abbreviations: BMT: bimodality therapy, GERD: gastroesophageal reflux disease, M: mucinous, NE: neuroendocrine; NOS: not otherwise specified; NA: not available, SRC: signet ring cell