Fig. 1.

Pancreatic histology of congenital hyperinsulinism in Turner syndrome. a, b Appearance of pancreatic islets in case 3 and case 7 with Turner syndrome and hyperinsulinism. c Pancreas of infant with diffuse KATP hyperinsulinism. d Normal islet in the unaffected region of pancreas from an infant operated on for focal hyperinsulinism. Histopathology of the 2 Turner syndrome cases and the KATP hyperinsulinism case shows similar changes of scattered islet cell nucleomegaly (arrows) and normal lobular parenchymal architecture typical of diffuse hyperinsulinism. HE staining. 40× magnification.