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. 2018 May 12;7:77–92. doi: 10.1007/s40204-018-0087-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Bioprinting of stem cells for the treatment of skin wounds. a: A schematic describes the approach by which amniotic fluid-derived stem cells (AFSC) are bioprinted in order to increase healing of a full-thickness skin wound. Wounds containing the deposited gels with green fluorescent protein-tagged AFSC were harvested after 24 h of post-printing and analyzed with confocal microscopy. Images revealed evenly distributed cells in the gels, as viewed from the top b or from the side (c). d: Gross histology images illustrating wound closure in gel-only, MSC, and AFS treatments. e: Percentage of unhealed wound remaining at the day of surgery, after one and 2 weeks. Abbreviations: AFS amniotic fluid-derived stem cells, AFSC amniotic fluid-derived stem cell, MSC mesenchymal stem cell. Adopted with permission from (Skardal et al. 2012)