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. 2018 Jul 31;8:11512. doi: 10.1038/s41598-018-29985-4

Table 4.

Prospective association between average alcohol consumption and Center for Epidemiologic Studies Depression Scale (CES-D) and the General Health Questionnaire-12 (GHQ-12) scores for older adults followed-up for 7.4 years; English Longitudinal Study of Ageing (ELSA).

CESD GHQ-12
n % Model 1 PRR (95% CI) Model 2 PRR (95% CI) n % Model 1 PRR (95% CI) Model 2 PRR (95% CI)
Average alcohol consumption 3971 Average alcohol consumption 3360
Never drinker 219 5.5 Ref. Ref. Never drinker 161 4.8 Ref. Ref.
Ex-drinker 188 4.7 1.16 (0.96–1.41) 1.11 (0.91–1.35) Ex-drinker 156 4.6 0.87 (0.59–1.30) 0.81 (0.54–1.21)
Moderate drinker 3146 79.2 0.95 (0.83–1.09) 0.92 (0.79–1.06) Moderate drinker 2688 80.0 0.77 (0.57–1.04) 0.75 (0.55–1.01)
Heavy drinker 418 10.5 1.05 (0.88–1.26) 1.00 (0.84–1.20) Heavy drinker 355 10.6 0.88 (0.61–1.27) 0.84 (0.58–1.21)

PRR: Prevalence rate ratios; CI: Confidence interval.

Model 1: Adjusted for the age, sex, educational level (≤primary, secondary, university) and baseline CESD scores or GHQ-12 scores.

Model 2: Adjusted additionally for tobacco smoking (never/former/current), physical activity, BMI (≤25, 25–29.9, ≥30 kg/m2), cardiovascular disease, respiratory disease, osteomuscular disease, diabetes, and cancer.