Table 4.

ASC OR in first-born children of women with PCOS in the CPRD

	PCOS			Control			Unadjusted	Model 1	Model 2
	ASC	Total	Prevalence (%)	ASC	Total	Prevalence (%)	OR (95% CI)	OR (95% CI)	OR (95% CI)
Total	104	8588	1.21	314	41127	0.76	1.60 (1.28–2.00)*	1.48 (1.18–1.87)*	1.35 (1.06–1.73)**
Male	90	4417	2.04	267	21098	1.27	1.63 (1.28–2.08)*	1.53 (1.20–1.97)*	1.42 (1.09–1.84)***
Female	14	4171	0.34	47	20029	0.23	1.43 (0.79–2.60)	1.21 (0.64–2.25)	1.05 (0.54–2.06)

Model 1 = adjusted for maternal age (at childbirth), depression, anxiety, schizophrenia-related illness

Model 2 = adjusted for maternal age (at childbirth), depression, anxiety, schizophrenia-related illness, complications at childbirth, obesity, diabetes, and gestational diabetes

*p-value < 0.001; **p-value < 0.05; ***p-value < 0.01