Figure 5. Effect of KLF2‐mediated increases in CB chemoreflex sensitivity on arrhythmia incidence in CHF rabbits.

A, representative tachograms illustrating increased arrhythmia incidence in CHF, and the salutary effect of CB KLF2 transfection. B, ECG traces taken during the period indicated by the black bar in A. C, cross‐sectional and longitudinal summary data for the arrhythmia index. n = 8 rabbits per group, except scrambled siRNA (n = 6). ^* P < 0.05 vs. pre‐pace. ^# P < 0.05 vs. CHF (within group, longitudinal). ^† P < 0.05 vs. CHF‐empty. Results are illustrated as a scatter plot with mean indicated by the horizontal black bar. For longitudinal data, individual animals were assigned a specific colour, which may be observed at each respective timepoint.