Table 3.
Baseline cardiovascular variables
| Sham | Pre | Post |
|---|---|---|
| MAP (mmHg) | 66 ± 2 | 70 ± 8 |
| HR (bpm) | 200 ± 13 | 201 ± 9 |
| CHF‐empty | Pre‐pace | CHF | CHF post‐virus |
|---|---|---|---|
| MAP (mmHg) | 71 ± 5 | 62 ± 5 | 62 ± 9 |
| HR (bpm) | 205 ± 6 | 222 ± 4* | 224 ± 8* |
| CHF‐KLF2 | Pre‐pace | CHF | CHF post‐virus |
|---|---|---|---|
| MAP (mmHg) | 78 ± 5 | 66 ± 7 | 62 ± 8* |
| HR (bpm) | 209 ± 7 | 225 ± 11 | 193 ± 5*† |
| Scrambled siRNA | Pre‐virus | Post‐virus |
|---|---|---|
| MAP (mmHg) | 76 ± 7 | 68 ± 10 |
| HR (bpm) | 204 ± 5 | 198 ± 11 |
| KLF2 siRNA | Pre‐virus | Post‐virus |
|---|---|---|
| MAP (mmHg) | 74 ± 7 | 82 ± 6 |
| HR (bpm) | 203 ± 6 | 210 ± 6 |
MAP = mean arterial pressure, HR = heart rate. n = 8 rabbits per group, except scrambled siRNA (n = 6). * P < 0.05 compared to respective baseline condition (pre‐pace or pre‐virus), † P < 0.05 compared to CHF, # P < 0.05 compared to CHF‐empty.