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. 2018 May 19;596(15):3217–3232. doi: 10.1113/JP275804

Figure 1. Enhancement of SNA following AIH is mediated by the RAS.

Figure 1

Effect of AIH on AP and SNA in (A) saline‐ and (B) losartan‐treated rats. C, group data for the change in SNA 60 min post‐AIH (**** P < 0.0001 vs. Time control; †††† P < 0.0001 vs. AIH + Saline). D, effect of losartan on the changes in the acute sympathetic chemoreflex caused by AIH. E, group data for the change in acute sympathetic chemoreflex (**** P < 0.0001 vs. Time control; †††† P < 0.0001 vs. AIH + Saline). F, effects of AIH on AP and SNA in a rat pre‐treated with aliskiren. G, group data for the change in SNA 60 min post‐AIH in aliskiren treated rats (*** P < 0.001 vs. AIH + Saline). H, grouped data of the effect of aliskiren on the changes in the acute sympathetic chemoreflex caused by AIH (** P < 0.01 vs. AIH + Saline).