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. 2018 Jan 4;596(15):3149–3169. doi: 10.1113/JP275001

Figure 8. ROS (O2·¯), but not H2O2, is involved in sensory LTF induction evoked by AIH‐Hc in naïve CB.

Figure 8

A and B, average integrated CSN activity (mean ± SEM; n = 5) showing that ROS scavenger MnTMPyP (25 μm) applied throughout (red arrows) prevents sensory LTF but failed to suppress sensory LTF 60 min after the last hypoxia‐hypercapnia bout. C and D, average integrated CSN activity (mean ± SEM; n = 5) demonstrating the H2O2 scavenger PEG‐catalase (200 U ml−1) had no effect when applied either the induction or maintenance phase of sensory LTF. E, summary data of MnTMPyP and catalase applied throughout and after sensory LTF induction. P values were determined by comparing CSN activities with basal responses (dashed line) before AIH‐Hc stimuli. Data are the mean ± SEM; n = 5.