Table 1.
Background O2 | Treatment time | (Torr) | O2 saturation (%) | (Torr) | pH | MAP (mmHg) |
---|---|---|---|---|---|---|
Normoxia | Pre‐AIH‐Hc | 86.8 ± 7.1 | 94.3 ± 2.0 | 39.7 ± 2.1 | 7.48 ± 0.02 | 99 ± 3 |
30 min | 83.5 ± 4.1 | 93.0 ± 1.4 | 38.8 ± 1.6 | 7.49 ± 0.02 | 107 ± 6 | |
60 min | 81.7 ± 4.4 | 92.0 ± 1.3 | 39.3 ± 1.9 | 7.48 ± 0.01 | 102 ± 3 | |
90 min DMSO | 79.3 ± 4.4 | 92.0 ± 1.5 | 39.7 ± 1.7 | 7.46 ± 0.01 | 106 ± 3 | |
Pre‐AIH‐Hc | 81.2 ± 5.1 | 92.4 ± 1.6 | 41.5 ± 1.8 | 7.48 ± 0.02 | 90 ± 3 | |
30 min | 79.0 ± 5.8 | 91.4 ± 2.4 | 41.8 ± 1.5 | 7.52 ± 0.04 | 93 ± 2 | |
60 min | 80.3 ± 3.8 | 92.8 ± 0.8 | 40.6 ± 1.0 | 7.48 ± 0.01 | 96 ± 3 | |
90 min AMG9810 | 79.3 ± 4.4 | 92.0 ± 1.5 | 39.7 ± 1.7 | 7.47 ± 0.01 | 94 ± 3 | |
Hyperoxia | Pre‐AIH‐Hc | 496.8 ± 10.8 | 100 ± 0 | 42.3 ± 1.9 | 7.42 ± 0.01 | 113 ± 6 |
30 min | 455.8 ± 36.6 | 100 ± 0 | 41.0 ± 2.3 | 7.41 ± 0.01 | 108 ± 8 | |
60 min | 469.5 ± 21.3 | 100 ± 0 | 40.3 ± 1.2 | 7.41 ± 0.01 | 105 ± 6 | |
90 min DMSO | 469.8 ± 24.8 | 100 ± 0 | 43.7 ± 2.8 | 7.39 ± 0.02 | 112 ± 8 | |
Pre‐AIH‐Hc | 491.0 ± 7.1 | 100 ± 0 | 40.7 ± 1.3 | 7.43 ± 0.01 | 110 ± 3 | |
30 min | 467.0 ± 13.9 | 100 ± 0 | 41.2 ± 1.2 | 7.43 ± 0.01 | 119 ± 4 | |
60 min | 483.0 ± 18.2 | 100 ± 0 | 41.0 ± 1.1 | 7.43 ± 0.01 | 117 ± 4 | |
90 min AMG9810 | 492.3 ± 10.6 | 100 ± 0 | 40.2 ± 1.3 | 7.42 ± 0.01 | 113 ± 3 |