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. 2018 Jul 25;9:1713. doi: 10.3389/fimmu.2018.01713

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Copyright © 2018 Huang, He, Liang, Hu, Jiang, Yang, Mei, Zhu, Yu, Kijlstra, Yang and Hou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TCDD treatment decreased apoptotic cell death in the retinas of experimental autoimmune uveitis mice. (A) Left, representative TdT-mediated dUTP nick end labeling (TUNEL) images of eye sections in naive, vehicle, and TCDD-treated mice. Scale bar, 30 µm. Right, quantification of TUNEL-positive cells (n = 4/group; mean ± SD;^*** p < 0.001; one-way ANOVA). (B) Upper, representative western blotting images of cleaved caspase-3, Bcl-2 associated X protein (Bax), and Bcl-2 in retinas of naive, vehicle, and TCDD-treated mice. Lower, quantifications of relative fold change of cleaved caspase-3, Bax, and Bcl-2 expressions (n = 4/group; mean ± SD;^* p < 0.05; **p < 0.01; ***p < 0.001; one-way ANOVA).