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. 2018 Jul 25;9:1713. doi: 10.3389/fimmu.2018.01713

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Copyright © 2018 Huang, He, Liang, Hu, Jiang, Yang, Mei, Zhu, Yu, Kijlstra, Yang and Hou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TCDD treatment downregulated pro-inflammatory cytokines in experimental autoimmune uveitis (EAU) mice. (A–C) Enzyme-linked immunosorbent assay (ELISA) for testing the protein level of tumor necrosis factor-α (TNF-α), interleukin (IL)-6, and IL-1β in the plasma of AhR^−/− and AhR^+/+ EAU mice (n = 4/group; mean ± SD;^* p < 0.05; ***p < 0.001; unpaired Student’s t-test). (D–F) ELISA for detecting the protein level of TNF-α, IL-6, and IL-1β in the plasma of naive, vehicle, and TCDD-treated mice (n = 4/group; mean ± SD;^* p < 0.05, **p < 0.01; one-way ANOVA).