Table 3.
Muscle deoxygenation overshoot during the first minutes of knee‐extension exercise
| BDC | N‐BR | H‐BR | H‐AMB | |
|---|---|---|---|---|
| Amplitude Δ[deoxy(Hb + Mb)] overshoot (% ischaemia) | 0.3 ± 1.0 | 4.3 ± 3.5* | 4.4 ± 4.2* | 0.3 ± 1.2 |
| Area under Δ[deoxy(Hb + Mb)] overshoot (% s) | 3.3 ± 10.5 | 104.8 ± 85.0* | 93.2 ± 107.7* | 3.5 ± 11.4 |
| Area under Δ[deoxy(Hb + Mb)] response (% s) | 696 ± 392 | 715 ± 308 | 701 ± 418 | 747 ± 357 |
| Δ[deoxy(Hb + Mb)] overshoot (% total response) | 0.5 ± 1.8 | 26.4 ± 17.6* | 24.9 ± 22.1* | 0.4 ± 1.4 |
Data are the mean ± SD. BDC, baseline data collection; N‐BR, normoxic bed rest; H‐BR, hypoxic bed rest; H‐AMB, hypoxic ambulatory confinement. Amplitude and area under muscle deoxygenation (Δ [deoxy(Hb + Mb)]) overshoot (expressed as a percentage of the maximal muscle deoxygenation during transient limb ischaemia) were measured during the first 2 min of constant work rate knee extension.
The ‘overshoot component’ was calculated as the area of the deoxygenation overshoot relative to the overall area of the Δ[deoxy(Hb + Mb)] response. *Significantly different from BDC.