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. 2018 Jan 4;596(15):3087–3100. doi: 10.1113/JP274833

Figure 4. Carotid body ablation (CBA) prevents LT‐IH‐evoked ROS and AOE gene repression in the nTS and RVLM.

Figure 4

Micro‐punches of nTS, RVLM were obtained from sham‐operated rats exposed to room air; sham‐operated rats exposed to 30 days of IH with intact CB (LT‐IH), and CBA rats exposed to 30 days of IH (LT‐IH + CBA). A, malondialdehyde (MDA) levels (index of ROS). B and C, AOE gene repression (Sod1, Sod2, superoxide dismutase 1 and 2; Cat, catalase; Txnrd2, thioredoxin reductase; Prdx4, peroxiredoxin 4; Gpx2, glutathione peroxidase 2) in the nTS (B) and RVLM (C). Data presented as means ± SEM, n = 9 rats per group; ** P < 0.01; * P < 0.05; ns, not significant, P > 0.05.