Table 3.

Correlations between different types of miRNA measurement readouts.

(A) miRNA marker change following exercise training intervention (n = 31 pairs).
X – Variable	miR-22/miR451	miR-22/miR451	miR-22/miR451	miR-22/spike	miR-451/spike	miR-22/miR451
Y – Variable	miR-22/spike	miR-451/spike	miR-21/spike	miR-21/spike	miR-21/spike	miR-22 + miR-21/miR- 451 + spike
Spearman’s R	0.3156	-0.348	0.09699	0.704	0.629	0.5986
P-Value	0.0838	0.055	0.6037	<0.0001	0.0002	0.0004
(B) miRNA marker change following nightly oxygen intervention (n = 21 pairs).
X – Variable	miR-22/miR451	miR-22/miR451	miR-22/miR451	miR-22/spike	miR-451/spike	miR-22/miR451
Y – Variable	miR-22/spike	miR-451/spike	miR-21/spike	miR-21/spike	miR-21/spike	miR-22 + miR-21/miR-451 + spike
Spearman’s R	0.7636	-0.2558	0.3143	0.5221	0.2494	0.8688
P-Value	<0.0001	0.2630	0.1653	0.0152	0.2757	<0.0001

Correlations and significance were calculated with Spearman’s rank correlation test on the fold-change after training relative to baseline, or oxygen relative to placebo, respectively. A p < 0.05 was considered significant (bold).