Fig. 1.

Serum beta hydroxybutyrate and glucose levels recorded over time (days) during KD. Serum glucose plotted from the left y-axis values with 70 mg/dL (hypoglycemia threshold) represented with black dotted line. Serum beta hydroxybutyrate levels plotted from right y-axis values with 0.6 mmol/L (upper limit of normal) represented with grey dashed line. SGLT2 inhibitor introduced on day 16 post KD represented by the black diamond with ketosis occuring in 7 days. Initiation of lorazepam infusion (propylene glycol source) is represented by a black square on day 33 post KD with subsequent normalization of beta hydroxybutyrate.