Table 2.
Multivariate Cox regression analysis of prognostic factors of 178 stage IIA ESCC patients
| Parameters | Five‐year OS | Five‐year LMR | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Gender (male vs. female) | 1.271 (0.845–1.912) | 0.250 | 1.246 (0.841–1.846) | 0.273 |
| Age (> 50 vs. ≤ 50 years) | 0.865 (0.578–1.293) | 0.479 | 0.837 (0.567–1.236) | 0.372 |
| Tumor size (≥ 3 cm vs. < 3 cm) | 0.472 (0.236–0.946) | 0.034 | 0.445 (0.233–0.852) | 0.014 |
| T status (T2 vs. T3) | 3.781 (1.847–7.739) | 0.000 | 4.325 (2.200–8.503) | 0.000 |
| Differentiation degree (low vs. mid‐high) | 1.591 (1.064–2.377) | 0.024 | 1.483 (1.003–2.192) | 0.048 |
| FOXM1 (low expression vs. overexpression) | 1.661 (1.100–2.508) | 0.016 | 1.877 (1.252–2.813) | 0.002 |
Bold values indicate P < 0.05. CI, confidence interval; ESCC, esophageal squamous cell carcinoma; HR, hazard ratio; LMR, lymphatic metastatic recurrence; OS, overall survival.