Table 2.
Diagnostic performance in subgroup analysis
| Serum | BAF/sputum | |||||
|---|---|---|---|---|---|---|
| Diagnostic index | Point estimate | 95% CI | I2 | Point estimate | 95% CI | I2 |
| Sensitivity | 0.37 | 0.34–0.40 | 89.8% | 0.59 | 0.55–0.62 | 71.7% |
| Specificity | 0.95 | 0.93–0.96 | 72.5% | 0.84 | 0.81–0.87 | 93.1% |
| +LR | 5.46 | 3.43–8.69 | 39.6% | 6.15 | 2.81–13.46 | 89.6% |
| −LR | 0.64 | 0.57–0.73 | 86.9% | 0.49 | 0.51–0.57 | 64.2% |
| DOR | 9.41 | 5.67–15.62 | 32.5% | 12.32 | 5.86–25.94 | 73.0% |
| AUC | 0.78 | 0.74–0.82 | — | 0.71 | 0.69–0.77 | — |
+LR, positive likelihood ratio; ‐LR, negative likelihood ratio; AUC, area under the curve; BAF, bronchoalveolar fluid; CI, confidence interval; DOR, diagnostic odds ratio.