Table 2.

Overall and disease‐free survival according to genotypes in patients with non‐small cell lung cancer

				Overall survival				Disease‐free survival
Variant	Position	Genotype	No. of cases	No. of deaths (%)	5Y‐OSR (%)†	HR (95% CI)‡	P ‡	No. of events (%)	5Y‐DFSR (%)†	HR (95% CI)‡	P ‡
rs9642391	ivs19+2851	CC	285	96 (33.7)	56	1.00		140(49.1)	41	1.00
		CG	313	83 (26.5)	63	0.70 (0.52–0.94)	0.02	145(46.3)	44	0.83 (0.66–1.05)	0.13
		GG	90	18 (20.0)	67	0.49 (0.30–0.82)	0.01	35(38.9)	48	0.67 (0.46–0.98)	0.04
		Dominant				0.65 (0.49–0.86)	0.003			0.79 (0.63–0.99)	0.04
		Recessive				0.59 (0.36–0.96)	0.04			0.74 (0.52–1.06)	0.10
		Codominant				0.70 (0.56–0.87)	0.001			0.82 (0.70–0.97)	0.02

^† Proportion of survival derived from Kaplan–Meier analysis.

^‡ Calculated using multivariate Cox proportional hazard models adjusted for age, gender, smoking status, tumor histology, stage, and adjuvant therapy.

5Y‐DFSR, 5‐year disease‐free survival rate; 5Y‐OSR, 5‐year overall survival rate; CI, confidence interval; HR, hazard ratio.