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. 2018 Jun 13;9(8):939–949. doi: 10.1111/1759-7714.12767

Figure 1.

Figure 1

OIP5‐AS1 was overexpressed in lung cancer tissues and was associated with tumor growth and prognosis. (a) OIP5‐AS1 was upregulated in lung adenocarcinoma (LUAD) and lung squamous cell cancer (LUSC) compared to adjacent normal tissue (P < 0.01). (b) OIP5‐AS1 expression and tumor size (40 vs. 40). (c) OIP5‐AS1 and Ki67 expression rates (40 vs. 40). (d) No difference in OIP5‐AS1 expression between cells with and without lymph node metastasis was observed. (e) OIP5‐AS1 expression level is associated with poor lung cancer prognosis and (f) lower total survival rate in patients positive and negative for lymph node metastasis (negative: OIP5‐AS1high n = 27, OIP5‐AS1low n = 27; positive: OIP5‐AS1high n = 11, OIP5‐AS1low n = 11). (g) High OIP5‐AS1 expression leads to lower total survival rate both in LUAD and LUSC patients (LUAD: OIP5‐AS1high n = 31, OIP5‐AS1low n = 31; LUSC: OIP5‐AS1high n = 9, OIP5‐AS1low n = 9). HR, hazard ratio.