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Surface plasmon resonance results of MAb 6E4 antibody with five sugars
| MAb | SPR result with the following sugara: |
||||
|---|---|---|---|---|---|
| KDO | Neu5Ac | Neu5Gc | Acα2-3SLN | Gcα2-3SLN | |
| 6E4 | 11.5 ± 1.1 nM | 3.45 ± 2.1 µM | 9.33 ± 2.2 µM | NCDI | NCDI |
SPR results of MAb 6E4 with free KDO, Neu5Ac, Neu5Gc, and α2-3 sialylactosamine (2-3SLN) containing either an acetyl group (Acα2-3SLN) or glycolyl group (Gcα2-3SLN). NCDI, no concentration-dependent interaction.
