FIG 3 .

L. plantarum does not trigger a proliferative response in adult fly intestines. (A) Schematic representation of gnotobiotic fly generation and experimental timeline. “Abx” indicates duration of antibiotic treatment. Sucrose and L. plantarum show feeding regimes for the respective groups. Green circles indicate times at which samples were processed. (B and C) Quantitative real-time PCR analysis of expression of the EGF-type growth factor spitz (B) and the spitz-activating endopeptidase rhomboid (C) from the dissected guts of adult CR, GF, and L. plantarum-associated flies. Each time point represents five independent measurements. P values are the results of pairwise comparisons from a one-way ANOVA.