FIG 2.

Cross-reactivity of HIV-1-specific CTL clones against other HIV-1 epitopes. HIV-1-specific CTL clones were tested against panels of known HIV-1 epitopes of the same HLA-I restriction, as shown in Fig. 1. Cross-reactivity was defined as observed specific lysis at ≥20% of specific lysis against the index epitope. The CTL clones and peptides are grouped according to HLA-I restriction. Black squares indicate the index epitope, gray squares indicate cross-reactivity, and white squares indicate lack of cross-reactivity.