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Susceptibilities of HIV-1 strains carrying WT or MAX protease variants to ATV
| Protease | ATV IC50 (nM) (fold change) |
|---|---|
| WT | 1.8 ± 1.2 (1) |
| MAX | 1.6 ± 0.4 (0.9) |
| WTS37P | 2.2 ± 1.0 (1.2) |
| MAXS37P | 2.2 ± 1.4 (1.2) |
| WTG48L | 14.4 ± 0.5 (8.1) |
| MAXG48L | 14.4 ± 1.4 (8.1) |
| WTQ58E | 4.6 ± 2.5 (2.6) |
| MAXQ58E | 5.6 ± 3.8 (3.2) |
| WTI84V | 1.3 ± 0.9 (0.7) |
| MAXI84V | 1.5 ± 0.8 (0.8) |
| WTL89I | 1.5 ± 0.5 (0.8) |
| MAXL89I | 2.1 ± 0.6 (1.2) |
