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Mean dN/dS values for major coding regions of H3N2 CIV and H3N2 AIV. All H3N2 AIV sequences available in the database were included. Only full genomes of nonreassorted CIVs were analyzed. NS1 contains a portion of the NS2 alternative reading frame. It should be noted that estimates for the shorter segments (M1 and NS1) show variance, especially among U.S. viruses that have circulated for a short period and accumulated only a small number of nucleotide substitutions.
