Table 3.
Within- and between-group comparisons of cardiometabolic risk factors during weight-loss intervention phase
| Outcome measures | Group | Baseline Mean (SD) | 6 month Mean (SD) | Change within-group | p-valuea | Mean Difference of change Between group | p-valueb |
|---|---|---|---|---|---|---|---|
| MD (95% CI) | MD (95% CI) | ||||||
| FPG (mmol/L) | Control (n=114) | 5.64 (1.03) | 5.58 (1.28) | -0.05 (-0.25, 0.14) | 0.569 | 0.06 (-0.23, 0.34) | 0.692 |
| Intervention (n=129) | 5.63 (1.45) | 5.51 (0.96) | -0.11 (-0.32, 0.10) | 0.287 | |||
| Triglycerides (mmol/L) | Control (n=114) | 1.35 (0.66) | 1.44 (0.72) | 0.09 (-0.04, 0.22) | 0.193 | -0.01 (-0.20, 0.18) | 0.906 |
| Intervention (n=129) | 1.35 (0.67) | 1.45 (0.63) | 0.10 (-0.04, 0.23) | 0.155 | |||
| Total cholesterol (mmol/L) | Control (n=114) | 5.70 (1.09) | 5.43 (0.97) | -0.27 (-0.42, -0.11) | 0.001** | -0.06 (-0.28, 0.17) | 0.620 |
| Intervention (n=129) | 5.59 (1.02) | 5.38 (0.85) | -0.21 (-0.38, -0.05) | 0.012* | |||
| HDL-C (mmol/L) | Control (n=114) | 1.38 (0.23) | 1.33 (0.23) | -0.05 (-0.10, -0.01) | 0.011* | -0.05 (-0.11, 0.01) | 0.103 |
| Intervention (n=129) | 1.31 (0.23) | 1.31 (0.25) | 0.00 (-0.05, 0.04) | 0.811 | |||
| LDL-C (mmol/L) | Control (n=114) | 4.59 (1.32) | 4.45 (1.09) | -0.14 (-0.37, 0.09) | 0.223 | -0.09 (-0.38, 0.19) | 0.526 |
| Intervention (n=129) | 4.44 (1.11) | 4.39 (0.94) | -0.05 (-0.23, 0.13) | 0.585 | |||
| LDL-C/HDL-C ratio | Control (n=114) | 3.35 (0.91) | 3.43 (0.91) | 0.07 (-0.12, 0.25) | 0.486 | 0.04 (-0.12, 0.28) | 0.741 |
| Intervention (n=129) | 3.43 (0.86) | 3.43 (0.94) | 0.03 (-0.13, 0.18) | 0.748 | |||
| TC/HDL-C ratio | Control (n=114) | 4.15 (0.71) | 4.18 (0.79) | -0.02 (-0.14, 0.11) | 0.82 | 0.05 (-0.17, 0.27) | 0.642 |
| Intervention (n=129) | 4.30 (0.70) | 4.25 (0.88) | -0.07 (-0.24, 0.10) | 0.432 |
Notes: Boldface indicates statistically significance *p<0.05, **p<0.01
Mean differences within group and between group are in mean (95% CI), a negative change indicates a fall in average from baseline to 6 month
aPaired t- test (between baseline and 6-month measurement), significant at p<0.05
bIndependent t-test, significant at p<0.05
Abbreviations: SD standard deviation, MD mean difference, FPG fasting plasma glucose, LDL-C Low-density lipoprotein-cholesterol, HDL-C High-density lipoprotein-cholesterol