Table 3.
Factors related to the development of hepatic encephalopathy in patients with cirrhosis after an acute episode of variceal bleeding. Univariate analysis.
| Characteristic | Without HE | With HE | OR (95% CI) | P |
|---|---|---|---|---|
| (n = 59) | (n = 28) | |||
| Rebleeding, n (%) | 7 (11.9) | 15 (53.6) | 8.6 (2.9 - 25.3)∗ | <0.0001 |
|
| ||||
| Decompensated cirrhosis CHILD B/C, n (%) | 35 (59.3) | 24 (85.7) | 4.1 (1.3 - 13.4)∗ | 0.01 |
|
| ||||
| SBP development, n (%) | 2 (3.4) | 1 (3.6) | 1.1 (0.09 - 12.2) | 1.00 |
|
| ||||
| Primary prophylaxis with any anti-ammonium drug, n (%) | 49 (83%) | 16 (57.1%) | 0.2 (0.09 - 0.7)∗∗ | 0.009 |
|
| ||||
| Gastric variceal bleeding source, n (%) | 9 (15.3%) | 3 (10.7%) | 0.7 (0.2 - 2.7) | 0.74 |
CI: confidence interval; HE: hepatic encephalopathy; OR: odds ratio; SBP: spontaneous bacterial peritonitis.
Statistical significance: P ≤ 0.05. ∗Risk factor. ∗∗Protective factor.