Table 1.
Geographical distribution and population structure of MTBC in Ghana by spoligotyping.
| Rural, n (%) | Urban, n (%) | Combined, n (%)a | |
|---|---|---|---|
| MTBC isolates | 204 (8.8) | 2118 (91.2) | 2322 |
| Species distribution | |||
| M. tuberculosis | 172 (9.2) | 1698 (90.8) | 1870 (80.5) |
| M. africanum | 29 (6.6) | 410 (93.4) | 439 (18.9) |
| Animal | 3 (23.1) | 10 (76.9) | 13 (0.6) |
| Human adapted MTBC lineage distribution | |||
| Lineage_1 | 4 (10.5) | 34 (89.5) | 38 (1.6) |
| Lineage_2 | 14 (21.5) | 51 (78.5) | 65 (2.8) |
| Lineage_3 | 1 (3.8) | 25 (96.2) | 26 (1.1) |
| Lineage_4 | 153 (8.8) | 1588 (91.2) | 1741 (75.4) |
| Lineage_5 | 15 (5.2) | 274 (94.8) | 289 (12.5) |
| Lineage_6 | 14 (9.3) | 136 (90.7) | 150 (6.5) |
| Lineage_4 sub-lineage distribution | |||
| Cameroon | 77 (7.4) | 969 (92.6) | 1046 (60.1) |
| Ghana | 50 (13.3) | 326 (86.7) | 376 (21.6) |
| Haarlem | 12 (7.7) | 144 (92.3) | 156 (9.0) |
| LAM | 7 (14.0) | 43 (86.0) | 50 (2.9) |
| Uganda | 1 (2.5) | 39 (97.5) | 40 (2.3) |
| Other (S, U, X, NEW-1) | 5 (9.8) | 46 (90.2) | 51 (2.9) |
| Not determined | 1 (4.5) | 21 (95.5) | 22 (1.3) |
MTBC, Mycobacterium tuberculosis complex.
a
Proportions stated here are column-wise distributions with respect to the categories of species, lineages or sub-lineages.