Table 2b.
Clustering analysis stratified by study setting and lineages/major sub-lineage populations of MTBC.
Lineage | Isolates (n) |
Clustered cases (c) |
Clustered strains (nc) |
Single cases (s) |
Total strain types (s + c) |
Clustering ratea (%) |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Urban | Rural | Urban | Rural | Urban | Rural | Urban | Rural | Urban | Rural | Urban | Rural | |
Lineage 1 | 34 | 4 | 3 | 0 | 7 | 0 | 27 | 4 | 30 | 4 | 11.8 | 0 |
Lineage 2 | 51 | 14 | 5 | 1 | 33 | 4 | 18 | 10 | 23 | 11 | 54.9 | 21.4 |
Lineage 3 | 25 | 1 | 2 | 0 | 4 | 0 | 21 | 1 | 23 | 1 | 8 | 0 |
Lineage 4 | 1588 | 153 | 183 | 10 | 907 | 25 | 681 | 128 | 864 | 138 | 45.6 | 9.8 |
Cameroonb | 969 | 77 | 112 | 5 | 575 | 10 | 394 | 67 | 506 | 72 | 47.8 | 6.5 |
Ghanab | 326 | 50 | 32 | 4 | 182 | 12 | 144 | 38 | 176 | 42 | 46 | 16 |
Haarlemb | 144 | 12 | 20 | 1 | 81 | 3 | 63 | 9 | 83 | 10 | 42.4 | 16.7 |
LAMb | 43 | 7 | 6 | 0 | 25 | 0 | 18 | 7 | 24 | 7 | 44.2 | 0 |
Ugandab | 39 | 1 | 5 | 0 | 16 | 0 | 23 | 1 | 28 | 1 | 28.2 | 0 |
Lineage 5 | 274 | 15 | 49 | 0 | 137 | 0 | 137 | 15 | 186 | 15 | 32.1 | 0 |
Lineage 6 | 136 | 14 | 10 | 0 | 43 | 0 | 93 | 14 | 103 | 14 | 24.3 | 0 |
Summaryc | 2108 | 201 | 252 | 11 | 1131 | 29 | 977 | 172 | 1229 | 183 | 41.7 | 9 |
MTBC, Mycobacterium tuberculosis complex.
The clustering rate was used to estimate the recent transmission rate.
Major lineage 4 sub-population.
The summary was calculated using only the items in cells corresponding to the six main lineages.