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. 2018 Jul 9;19(Suppl 7):199. doi: 10.1186/s12859-018-2173-7

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Lipidomics Case Study: Overall Comparison. a Comparison of the ranking of the set of lipid species obtained from the overall measure of statistical significance via the RFM approach compared to the MRF approach. Lipids above the grey dashed line are ranked higher under RFM, whereas lipids below the dashed line are ranked higher under MRF. Colour of points indicates the associated type of each lipid species. b Lipids ranked according to the overall test of significance under MRF (one-way ANOVA of the predictive model). c Lipids grouped according to the set of effects included in the predictive model under MRF. d Lipids ranked according to the overall test of significance under RFM (one-way ANOVA of the saturated model). e Lipids grouped according to the set of effects included in the predictive model under RFM. Information provided in tabular form in Additional file 2 of the Supplementary Material