Table 1.
Odontogenesis | |||||||||
---|---|---|---|---|---|---|---|---|---|
Dental lamina | Bud stage | Cap stage | Bell stage | ||||||
BMP4 | FGF8 | BMP4 | FGF8 | BMP4 | FGF8 | BMP4 | FGF8 | ||
Ectodermal components | |||||||||
Basal cells | C | +++ | +++ | − | + | Ab | Ab | Ab | Ab |
N | + | + | + | + | Ab | Ab | Ab | Ab | |
Inner enamel epithelium | C | Ab | Ab | Ab | Ab | − | − | +++ | +++ |
N | Ab | Ab | Ab | Ab | + | + | + | + | |
Stratum intermedium | C | Ab | Ab | Ab | Ab | Ab | Ab | +++ | +++ |
N | Ab | Ab | Ab | Ab | Ab | Ab | + | + | |
Stellate reticulum | C | Ab | Ab | Ab | Ab | − | − | +++ | +++ |
N | Ab | Ab | Ab | Ab | + | + | + | + | |
Outer enamel epithelium | C | Ab | Ab | Ab | Ab | − | − | +++ | +++ |
N | Ab | Ab | Ab | Ab | + | + | + | + | |
Ectomesenchymal components | |||||||||
Stromal component | C | ++ | ++ | − | − | Ab | Ab | Ab | Ab |
N | + | + | + | − | Ab | Ab | Ab | Ab | |
Dental papilla | C | Ab | Ab | Ab | Ab | − | + | ++ | ++ |
N | Ab | Ab | Ab | Ab | − | + | ++ | ++ | |
Dental sac | C | Ab | Ab | Ab | Ab | − | + | ++ | ++ |
N | Ab | Ab | Ab | Ab | − | + | + | + |
C: cytoplasm; N: nucleus; Ab: absent.