Table 1.
Relationship between Wnt5a immunohistochemistry and methylation with clinicopathologic features of ovarian carcinoma.
| Clinicopathologic parameters | n | Protein expression | P | Methylation positive | P |
|---|---|---|---|---|---|
| Age (years) | |||||
| ≤48 | 34 | 14 (41.18) | >0.05 | 13 (38.24) | |
| >48 | 45 | 21 (46.47) | 18 (40) | >0.05 | |
| WHO grades | |||||
| G1 | 13 | 10 (76.92) | 0.005∗ | 5 (38.46) | |
| G2 | 29 | 13 (44.83) | 10 (34.48) | >0.05 | |
| G3 | 37 | 12 (32.43) | 16 (43.24) | ||
| FIGO stages | |||||
| I~II | 36 | 22 (61.11) | 0.006 | 9 (25) | |
| III~IV | 43 | 13 (30.23) | 22 (51.16) | 0.018 | |
| Histological types | |||||
| Serous adenocarcinoma | 50 | 22 (44) | >0.05 | 19 (38) | |
| Mucinous adenocarcinoma | 23 | 11 (47.83) | 9 (39.13) | >0.05 | |
| Others | 6 | 3 (50) | 2 (33.33) | ||
| Lymph node metastasis | |||||
| No | 38 | 20 (52.63) | 0.037 | 10 (26.32) | 0.024 |
| Yes | 41 | 15 (36.59) | 21 (51.22) |
∗The P value of G1 compared with that of G3.