Fig. 8.

An MLS with high reciprocal influences (RI) but with a low number of oscillating multi-omics is shown in (1). On this MLS, due to the effect of the treatments t, an oscillating multi-omic circuit is activated (orange links in the yellow circle) and is deactivated another one. The MLS become combined due to the effect of t because both the pattern and the pathway show oscillating multi-omics at the same time. Opposite, in (2), the effect of treatments activate and deactivate the same oscillating multi-omic circuits, but, due to the changed pattern elements order, only the pathway shows oscillating multi-omics, instead the pattern shows a low number of oscillations. In this case, the structures are defined competitor. The change of only two multi-omic values (p₃ and p₅) on the overall pathway and on the pattern (e₃ and e₅) affect the whole recurring multi-omic pattern and its MLS