Table 1.
Association between TNFAIP8 expression and clinicopathological characteristics of NSCLC patients
| Variable | All patients | TNFAIP8 expression | P | |
|---|---|---|---|---|
| High (%) | Low (%) | |||
| (n = 196) | (n = 106) | (n = 90) | ||
| Smoking | ||||
| Never | 93 | 53 (50) | 40 (44) | 0.438 |
| Ever | 103 | 53 (50) | 50 (56) | |
| Gender | ||||
| Male | 129 | 68 (64) | 61 (68) | 0.594 |
| Female | 67 | 38 (36) | 29 (32) | |
| Age (years) | ||||
| < 60 | 129 | 71 (67) | 58 (64) | 0.709 |
| ≥ 60 | 67 | 35 (33) | 32 (36) | |
| Differentiation | ||||
| Well | 18 | 12 (11) | 6 (7) | 0.263 |
| Moderate | 87 | 42 (40) | 45 (50) | |
| Poor | 91 | 52 (49) | 39 (43) | |
| Histological cell type | ||||
| Adenocarcinoma | 122 | 70 (66) | 52 (58) | 0.235 |
| Squamous cell carcinoma | 74 | 36 (34) | 38 (42) | |
| pStage | ||||
| I | 93 | 43 (40.5) | 50 (56) | 0.022* |
| II | 40 | 20 (19) | 20 (22) | |
| III | 63 | 43 (40.5) | 20 (22) | |
| pT classification | ||||
| T1 | 51 | 20 (19) | 31 (34) | 0.034* |
| T2 | 129 | 75 (71) | 54 (60) | |
| T3/4 | 16 | 11 (10) | 5 (6) | |
| Lymph node metastasis | 0.005* | |||
| Present | 82 | 54 (51) | 28 (31) | |
| Absent | 114 | 52 (49) | 62 (69) | |
| Adjuvant therapy | ||||
| Yes | 121 | 62 (58) | 59 (66) | 0.311 |
| No | 75 | 44 (42) | 31 (34) | |
Abbreviations: NSCLC non-small cell lung cancer, pTNM stage tumor, node, metastasis (pathological stage), pT pathological T stage, n number of patients. Ever: smoking at any time from the beginning of life. P value: the difference of clinicopathological characteristics between the TNFAIP8 high expression group and low expression group. *P < 0.05 was considered statistically significant